Route Description
The second of the original two routes that were created in 2004, Rockies travels north in the shadow of the Rocky Mountains through the United States and Canada. Passing through North Texas, Oklahoma, New Mexico, Colorado, Utah, Idaho, Wyoming, and Montana, the route then heads into the Canadian provinces and territories of Alberta, British Columbia, and the Yukon before passing into Alaska. The Rockies route visits many small and remote towns in addition to larger cities, bringing crucial knowledge and hope to communities affected by cancer off the beaten path. The route passes through Dallas, TX; Denver, CO; Salt Lake City, UT; Yellowstone National Park, WY; Bozeman, MT; Glacier National Park, MT; Calgary, AB; Prince George, BC; and Whitehorse, YT, before reaching Alaska.
2025 Rockies Route:
| Day | Day of week | Date | Rockies Ending Location |
| 0 | Friday | May-16 | Austin, TX |
| 1 | Saturday | May-17 | Georgetown, TX |
| 2 | Sunday | May-18 | Waco, TX |
| 3 | Monday | May-19 | Waxahachie, TX |
| 4 | Tuesday | May-20 | Dallas, TX |
| 5 | Wednesday | May-21 | Dallas, TX [REST] |
| 6 | Thursday | May-22 | Gainsville, TX |
| 7 | Friday | May-23 | Wynnewood, OK |
| 8 | Saturday | May-24 | Oklahoma City, OK |
| 9 | Sunday | May-25 | Oklahoma City, OK [REST] |
| 10 | Monday | May-26 | Watonga, OK |
| 11 | Tuesday | May-27 | Woodward, OK |
| 12 | Wednesday | May-28 | Guymon, OK |
| 13 | Thursday | May-29 | Clayton, NM |
| 14 | Friday | May-30 | Trinidad, CO |
| 15 | Saturday | May-31 | Pueblo, CO |
| 16 | Sunday | Jun-1 | Colorado Springs, CO |
| 17 | Monday | Jun-2 | Denver, CO |
| 18 | Tuesday | Jun-3 | Denver, CO – [REST] |
| 19 | Wednesday | Jun-4 | Estes Park/Rocky Mountain NP, CO |
| 20 | Thursday | Jun-5 | Steamboat Springs, CO |
| 21 | Friday | Jun-6 | Dinosaur NM, UT |
| 22 | Saturday | Jun-7 | Fruitland, UT |
| 23 | Sunday | Jun-8 | Salt Lake City, UT |
| 24 | Monday | Jun-9 | Salt Lake City, UT [REST] |
| 25 | Tuesday | Jun-10 | Logan, UT |
| 26 | Wednesday | Jun-11 | Pocatello, ID |
| 27 | Thursday | Jun-12 | Idaho Falls, ID |
| 28 | Friday | Jun-13 | Jackson, WY/Grand Teton NP, WY |
| 29 | Saturday | Jun-14 | Jackson, WY/Grand Teton NP, WY [REST] |
| 30 | Sunday | Jun-15 | Yellowstone NP, WY |
| 31 | Monday | Jun-16 | Big Sky, MT |
| 32 | Tuesday | Jun-17 | Bozeman, MT |
| 33 | Wednesday | Jun-18 | Helena, MT |
| 34 | Thursday | Jun-19 | Missoula, MT |
| 35 | Friday | Jun-20 | Kalispell, MT |
| 36 | Saturday | Jun-21 | Glacier NP, MT |
| 37 | Sunday | Jun-22 | Glacier NP, MT [REST] |
| 38 | Monday | Jun-23 | Claresholm, AB |
| 39 | Tuesday | Jun-24 | Calgary, AB |
| 40 | Wednesday | Jun-25 | Banff, AB [Canmore] |
| 41 | Thursday | Jun-26 | Banff NP, AB |
| 42 | Friday | Jun-27 | Jasper, AB |
| 43 | Saturday | Jun-28 | Jasper, AB [REST] |
| 44 | Sunday | Jun-29 | McBride, BC |
| 45 | Monday | Jun-30 | Purden Lake, BC |
| 46 | Tuesday | Jul-1 | Prince George, BC |
| 47 | Wednesday | Jul-2 | Vanderhoof, BC |
| 48 | Thursday | Jul-3 | Burns Lake, BC |
| 49 | Friday | Jul-4 | Burns Lake [REST] |
| 50 | Saturday | Jul-5 | Smithers, BC |
| 51 | Sunday | Jul-6 | Kitwanga, BC |
| 52 | Monday | Jul-7 | Meziadin Junction, BC |
| 53 | Tuesday | Jul-8 | Kinaskan Lake Provincial Park, BC |
| 54 | Wednesday | Jul-9 | Iskut, BC |
| 55 | Thursday | Jul-10 | Dease Lake, BC |
| 56 | Friday | Jul-11 | Dease Lake, BC [REST] |
| 57 | Saturday | Jul-12 | Jade City, BC |
| 58 | Sunday | Jul-13 | Rancheria, YT |
| 59 | Monday | Jul-14 | Teslin, YT |
| 60 | Tuesday | Jul-15 | Whitehorse, YT |
| 61 | Wednesday | Jul-16 | Whitehorse, YT |
| 62 | Thursday | Jul-17 | Haines Junction, YT |
| 63 | Friday | Jul-18 | Burwash Landing, YT |
| 64 | Saturday | Jul-19 | Beaver Creek, YT |
| 65 | Sunday | Jul-20 | Tok, AK |
| 66 | Monday | Jul-21 | Chistochina, AK |
| 67 | Tuesday | Jul-22 | Glennallen, AK |
| 68 | Wednesday | Jul-23 | Nelchina, AK |
| 69 | Thursday | Jul-24 | Wasilla, AK |
| 70 | Friday | Jul-25 | Anchorage, AK |